Scientists have confirmed the jab can trigger a very uncommon condition called Guillain-Barré Syndrome.
The condition is linked to infectious diseases and attacks the nervous system, causing a range of symptoms.
It can lead to numbness, weakness and pain, usually in the feet, hands and limbs and can spread to the chest and face.
Tens of millions of doses of the Oxford vaccine have been delivered and there have been just 432 reports of the side effect.
The vast majority of people who develop the syndrome recover but it is fatal for around one in 20.
The proportion of people likely to develop serious complications is miniscule when compared to the effects of Covid-19.
Figures published by the Office for National Statistics show there have now been 164,000 deaths registered in the UK where Covid-19 was mentioned on the death certificate.
The European equivalent of the medicines agency has previously added the syndrome to the list of side effects.
The MHRA followed suit after it determined ‘the most recent review of the available data the evidence of a possible association has strengthened’.
A government document read: ‘Up to October 13, the MHRA had received 432 reports of the syndrome with the COVID-19 Vaccine AstraZeneca and 26 reports of a related disease called Miller Fisher syndrome.
‘Up to the same date, the MHRA has received 59 reports of Guillain-Barre Syndrome following use of the Pfizer/BioNTech vaccine and 1 report of Miller Fisher syndrome and for the COVID-19 Vaccine Moderna there have been four reports of Guillain-Barré Syndrome.
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